High-dose dual antibiotic cement for hip hemiarthroplasty

This Bayesian re-analysis demonstrates that it is highly probable (> 90%) that there is at least some reduction of dSSI related to high-dose dual-antibiotic cement use when performing hemiarthroplasty; adding useful clinical nuance to the original trial findings in context of the noteworthy detrimental impact of dSSI in the study population. This study also highlights the potential benefits of a Bayesian approach to analysis due to improved interpretability of trial outcomes.

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Publication Details

Journal
The Bone & Joint Journal
Published
2025-09-01
DOI
https://doi.org/10.1302/0301-620x.107b9.bjj-2024-1364.r1
Citations
2
Primary Topic
Orthopaedic implants and arthroplasty
Type
article
Field-Weighted Citation Impact
4.01
Controls
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article

High-dose dual antibiotic cement for hip hemiarthroplasty

Jemma Hudson, Luke Farrow, Mike Reed, Alan M. George et al.
2 citations
The Bone & Joint Journal
Orthopaedic implants and arthroplasty
4.01
article

High-dose dual antibiotic cement for hip hemiarthroplasty

Jemma Hudson, Luke Farrow, Mike Reed, Alan M. George, Marion Campbell
article en
2 citations

Abstract

This Bayesian re-analysis demonstrates that it is highly probable (> 90%) that there is at least some reduction of dSSI related to high-dose dual-antibiotic cement use when performing hemiarthroplasty; adding useful clinical nuance to the original trial findings in context of the noteworthy detrimental impact of dSSI in the study population. This study also highlights the potential benefits of a Bayesian approach to analysis due to improved interpretability of trial outcomes.

The Bone & Joint JournalVol. 107-B(9)
University of Aberdeen (GB), Aberdeen Royal Infirmary (GB), Northumbria Healthcare NHS Foundation Trust (GB), University of York (GB), University of Arkansas at Fayetteville (US)
Openalex Percentile: Top 6%
Orthopaedic implants and arthroplasty
4.01
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High-dose dual antibiotic cement for hip hemiarthroplasty — Jemma Hudson, Luke Farrow, et al. · The Bone & Joint Journal (2025) | TGRS Research Map | TGRS