The impact of the tetralogy of Fallot primary correction technique on the frequency of reinterventions

The aim – to analyze the types of reinterventions after the total repair of tetralogy of Fallot and identify the factors influencing the risk of reoperations.Materials and methods. This study presents a single-center retrospective analysis of long-term outcomes of 1,441 total repair of tetralogy of Fallot performed from 2000 to 2023. The median patient age was 9,8 [3.3; 128] months (ranging from 0.1 to 204 months), and the median weight was 10.1 [3.3; 57] kg (ranging from 3.3 to 70 kg). Associated cardiac pathologies were diagnosed in 43,1 % of patients, while genetic anomalies were identified in 6.3 %. The TAP technique (the transannular patch) was applied in 61.2 % of cases, whereas NTAP (the non-transannular patch) – in 38.8 %. The overall mortality rate following primary total repair was 3.46 %. The long-term follow-up period averaged 107.3 ± 54.7 months (ranging from 13 to 241 months).Results. Surgical and percutaneous reintervention procedures (n = 320) were performed in 225 (16.5 %) patients, on average, 89.7±49.7 months (ranging from 8.7 to 204 months) after total repair. The most common indications for repeat procedures included pulmonary valve insufficiency requiring conduit implantation in the pulmonary artery position (53.3 %), pulmonary valve and branch stenosis (47.97 %), and residual right ventricular outflow tract obstruction (39.1 %).Conclusions. Correlation analysis revealed that the use of TAP is an independent risk factor for repeat surgeries (r = 0.726, p < 0.001). Meanwhile, the valve-sparing technique for right ventricular outflow tract obstruction repair in tetralogy of Fallot is associated with a lower risk of pulmonary valve insufficiency and the need for conduit implantation during long-term period.

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Journal
Cardiac Surgery and Interventional Cardiology
Published
2025-08-31
DOI
https://doi.org/10.31928/2664-3790-2025.2.1723
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

The impact of the tetralogy of Fallot primary correction technique on the frequency of reinterventions

Nadiya M. Rudenko, O. M. Romaniuk, О. В. Дудко, D. V. Kryvolap
Cardiac Surgery and Interventional Cardiology
Congenital Heart Disease Studies
article

The impact of the tetralogy of Fallot primary correction technique on the frequency of reinterventions

Nadiya M. Rudenko, O. M. Romaniuk, О. В. Дудко, D. V. Kryvolap
article en

Abstract

The aim – to analyze the types of reinterventions after the total repair of tetralogy of Fallot and identify the factors influencing the risk of reoperations.Materials and methods. This study presents a single-center retrospective analysis of long-term outcomes of 1,441 total repair of tetralogy of Fallot performed from 2000 to 2023. The median patient age was 9,8 [3.3; 128] months (ranging from 0.1 to 204 months), and the median weight was 10.1 [3.3; 57] kg (ranging from 3.3 to 70 kg). Associated cardiac pathologies were diagnosed in 43,1 % of patients, while genetic anomalies were identified in 6.3 %. The TAP technique (the transannular patch) was applied in 61.2 % of cases, whereas NTAP (the non-transannular patch) – in 38.8 %. The overall mortality rate following primary total repair was 3.46 %. The long-term follow-up period averaged 107.3 ± 54.7 months (ranging from 13 to 241 months).Results. Surgical and percutaneous reintervention procedures (n = 320) were performed in 225 (16.5 %) patients, on average, 89.7±49.7 months (ranging from 8.7 to 204 months) after total repair. The most common indications for repeat procedures included pulmonary valve insufficiency requiring conduit implantation in the pulmonary artery position (53.3 %), pulmonary valve and branch stenosis (47.97 %), and residual right ventricular outflow tract obstruction (39.1 %).Conclusions. Correlation analysis revealed that the use of TAP is an independent risk factor for repeat surgeries (r = 0.726, p < 0.001). Meanwhile, the valve-sparing technique for right ventricular outflow tract obstruction repair in tetralogy of Fallot is associated with a lower risk of pulmonary valve insufficiency and the need for conduit implantation during long-term period.

Cardiac Surgery and Interventional CardiologyVol. 14(2)
Ministry of Education and Science (UA), National University of Life and Environmental Sciences of Ukraine (UA), Shupyk National Healthcare University of Ukraine (UA), Ministry of Health (UA)
Openalex Percentile: Top 69%
Congenital Heart Disease Studies
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