Identification of Signal Source Neurons in Micro-Networks through High-Density Measurements

Fundamental properties of neuronal networks at the single-cell level can be understood by comprehensively capturing the activity of all neurons within the network. In this study, we constructed micro-networks on a high- density micro electrode array (HD-MEA) and performed electrical measurements of all neurons using a densely packed electrode configuration. We mapped the activity of individual neurons with cell positions on stained images.