A new experimental model of chronic pulpitis

In the specialized literature there are some reports containing information about experimental studies in chronic pulpitis. In one part of them, extracted human teeth are regarded as a variant of the experimental model. In another part, either highly organized animals (dogs) or rodents, whose incisors are constantly growing, were used as a biological object. This does not allow for full reproduction of the clinical situation of chronic pulpitis. The aim of this study is to develop an experimental model of chronic pulpitis in an animal subject, specifically a rabbit of the Chinchilla breed, that reflects actual clinical conditions at various stages of development, the trajectory of infectious agent propagation, and the formation of inflammatory focus, thereby allowing for the study of this pathological process in dynamics. Research methods: descriptive, experimental, and pathohistologic. The proposed experimental model of chronic pulpitis using a biological object‒a rabbit of the Chinchilla breed, according to the stages of development, the path of spread of the infectious agent and the formation of inflammatory focus‒fully corresponds to the real clinical conditions of chronic pulpitis. Due to the sufficient size of the rabbit’s teeth, jaw bones, and circulating blood volume, it is optimal for the realization of material sampling when performing pathohistological and laboratory studies in dynamics, both during the development of the pathological process and during itstreatment. This makes it economically justified.

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Publication Details

Journal
Proceedings of the National Academy of Sciences of Belarus Medical series
Published
2025-08-31
DOI
https://doi.org/10.29235/1814-6023-2025-22-3-239-245
Primary Topic
Myofascial pain diagnosis and treatment
Type
article
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article

A new experimental model of chronic pulpitis

Т.Н. Терехова, I. О. Pohodenko-Chudakova, Tatiana Pyko, Zh. A. Makarevich et al.
Proceedings of the National Academy of Sciences of Belarus Medical series
Myofascial pain diagnosis and treatment
article

A new experimental model of chronic pulpitis

Т.Н. Терехова, I. О. Pohodenko-Chudakova, Tatiana Pyko, Zh. A. Makarevich, K. S. Vorobʼyova
article en

Abstract

In the specialized literature there are some reports containing information about experimental studies in chronic pulpitis. In one part of them, extracted human teeth are regarded as a variant of the experimental model. In another part, either highly organized animals (dogs) or rodents, whose incisors are constantly growing, were used as a biological object. This does not allow for full reproduction of the clinical situation of chronic pulpitis. The aim of this study is to develop an experimental model of chronic pulpitis in an animal subject, specifically a rabbit of the Chinchilla breed, that reflects actual clinical conditions at various stages of development, the trajectory of infectious agent propagation, and the formation of inflammatory focus, thereby allowing for the study of this pathological process in dynamics. Research methods: descriptive, experimental, and pathohistologic. The proposed experimental model of chronic pulpitis using a biological object‒a rabbit of the Chinchilla breed, according to the stages of development, the path of spread of the infectious agent and the formation of inflammatory focus‒fully corresponds to the real clinical conditions of chronic pulpitis. Due to the sufficient size of the rabbit’s teeth, jaw bones, and circulating blood volume, it is optimal for the realization of material sampling when performing pathohistological and laboratory studies in dynamics, both during the development of the pathological process and during itstreatment. This makes it economically justified.

Proceedings of the National Academy of Sciences of Belarus Medical seriesVol. 22(3)
Belarusian State Medical University (BY)
Openalex Percentile: Top 76%
Myofascial pain diagnosis and treatment
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A new experimental model of chronic pulpitis — Т.Н. Терехова, I. О. Pohodenko-Chudakova, et al. · Proceedings of the National Academy of Sciences of Belarus Medical series (2025) | TGRS Research Map | TGRS