Biological age on pause. The effect of nutraceuticals on endothelial dysfunction and aging processes

Aging is an inevitable process that includes an imbalance between antioxidant defenses and reactive oxygen species, changes in protein and mitochondrial turnover, telomere shortening, cellular senescence, epigenetic changes, and stem cell exhaustion. These conditions are associated with mild to moderate inflammation, which always accompanies the aging process and age-related diseases. The results of numerous studies indicate the existence of a complex biomolecular mechanism associated with age-related vascular dysfunction, which leads to oxidative stress, vascular remodeling, and endothelial dysfunction.