Risk factors of linezolid-associated hyponatremia from a retrospective case–control study: decreased serum albumin as a selective predictor in elder patients
A decrease in ALB during linezolid therapy is a more selective predictor of hyponatremia than baseline ALB. Linezolid-induced hyponatremia is associated with adverse outcomes, highlighting the importance of monitoring serum sodium and ALB in patients receiving this therapy.
Authors
- Fei Zhao (ORCID: https://orcid.org/0000-0003-3107-1576)
- Ju Yang (ORCID: https://orcid.org/0000-0001-5305-7893)
- Bolin Zhu (ORCID: https://orcid.org/0000-0002-6846-566X)
- Pengfei Jin (ORCID: https://orcid.org/0000-0002-8908-2633)
- Di Chen (ORCID: https://orcid.org/0000-0002-6983-1641)
- Ming Zhao (ORCID: https://orcid.org/0000-0002-2273-4641)
- Yuanchao Zhu (ORCID: https://orcid.org/0000-0001-5646-3379)
- Liang Liang (ORCID: https://orcid.org/0000-0001-8331-5822)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Academia Sinica (TW)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1080/07853890.2025.2551822
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00