Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial

Authors

May Smith‐Hublou (ORCID: https://orcid.org/0000-0001-8797-4884)
Wagner Souza Leite (ORCID: https://orcid.org/0000-0001-5716-125X)
Nicholas J. Napoli (ORCID: https://orcid.org/0000-0002-9071-3965)
Wendy L. Olsen (ORCID: https://orcid.org/0000-0002-7607-8096)
Barbara K. Smith (ORCID: https://orcid.org/0000-0002-3255-7036)
James P. Wymer (ORCID: https://orcid.org/0000-0003-0809-2977)
Gordon S. Mitchell (ORCID: https://orcid.org/0000-0002-8489-1861)
Michael Pulley (ORCID: https://orcid.org/0000-0003-1879-725X)
Alicia K. Vose (ORCID: https://orcid.org/0000-0001-5502-266X)
Priscila Furtado Campos (ORCID: https://orcid.org/0000-0003-0194-7135)

Institutions

Universidade do Estado de Santa Catarina (BR)
University of Florida Health (US)
University of Florida (US)
Jacksonville University (US)
Appalachian State University (US)
University of Florida Health Science Center (US)
Florida College (US)

Publication Details

Journal: JMIR Research Protocols
Published: 2025-08-31
DOI: https://doi.org/10.2196/76105
Primary Topic: Amyotrophic Lateral Sclerosis Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial

May Smith‐Hublou, Wagner Souza Leite, Nicholas J. Napoli, Wendy L. Olsen et al.

Aug 31, 2025

JMIR Research Protocols

Amyotrophic Lateral Sclerosis Research

article

Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial

May Smith‐Hublou, Wagner Souza Leite, Nicholas J. Napoli, Wendy L. Olsen, Barbara K. Smith, James P. Wymer, Gordon S. Mitchell, Michael Pulley, Alicia K. Vose, Priscila Furtado Campos

August 31, 2025article en

Abstract

No abstract available for this paper.

JMIR Research ProtocolsVol. 14

Universidade do Estado de Santa Catarina (BR), University of Florida Health (US), University of Florida (US), Jacksonville University (US), Appalachian State University (US), University of Florida Health Science Center (US), Florida College (US)

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Openalex Percentile: Top 67%

Amyotrophic Lateral Sclerosis Research

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Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial — May Smith‐Hublou, Wagner Souza Leite, et al. · JMIR Research Protocols (2025) | TGRS Research Map | TGRS