Imaging Changes With or Without Neurologic Symptoms After Proton Therapy in Pediatric Posterior Fossa Tumors: Initial Experience of the Dutch National Cohort
The initial experience of PT for pediatric PF tumors in the Netherlands demonstrates post-PT contrast enhancement with associated symptoms in 15% of the patients, and an increased risk in patients aged <5 years and patients with a prescribed dose ≥59.4 GyE.
Authors
- Johannes A. Langendijk (ORCID: https://orcid.org/0000-0003-1083-372X)
- Abel Bregman (ORCID: https://orcid.org/0009-0001-7481-1733)
- John H. Maduro (ORCID: https://orcid.org/0000-0003-2458-8702)
- W Matysiak (ORCID: https://orcid.org/0000-0003-4552-1662)
- Enrica Seravalli
- Peter S.N. van Rossum (ORCID: https://orcid.org/0000-0003-4243-8388)
- Bianca A.W. Hoeben (ORCID: https://orcid.org/0000-0003-3026-8721)
- Hiska L. van der Weide (ORCID: https://orcid.org/0000-0001-6734-2345)
- Eelco W. Hoving (ORCID: https://orcid.org/0000-0002-5587-0439)
- Maarten H. Lequin (ORCID: https://orcid.org/0000-0001-7488-1734)
- Sabine Plasschaert (ORCID: https://orcid.org/0000-0003-3391-3618)
- Geert O. Janssens (ORCID: https://orcid.org/0000-0002-0331-713X)
- Jikke J. Rutgers (ORCID: https://orcid.org/0000-0003-3727-5326)
- Astrid van der Heide
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- University Medical Center Utrecht (NL)
- Princess Máxima Center (NL)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.08.046
- Citations
- 1
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- European Commission
- Universitair Medisch Centrum Utrecht
- Universitair Medisch Centrum Groningen