Urothelial carcinoma in situ of the entire urinary tract with invasion into seminal vesicle: A case report
Urothelial carcinoma in situ represents a high-grade, high-risk form of urothelial cancer which predominantly occurs within the bladder, rarely affecting other structures within the genitourinary system such as the seminal vesicle. Involvement could represent more advanced disease, necessitating more aggressive management. We present a case of CIS involving the entire urinary tract in a renal transplant patient who underwent a complete urinary tract extirpation (CUTE) for BCG-refractory CIS of the bladder. This case is unique, representing the first reported CUTE with malignant involvement of every site in the urinary tract.
Authors
- Andrew Redfern (ORCID: https://orcid.org/0000-0001-6728-8713)
- Alarick Picardo (ORCID: https://orcid.org/0000-0002-2542-9757)
- Cynthia Hawks (ORCID: https://orcid.org/0000-0001-7848-9537)
- Dickon Hayne (ORCID: https://orcid.org/0000-0002-4094-401X)
- Nicole Swarbrick (ORCID: https://orcid.org/0000-0002-1231-5742)
- Steve P. McCombie (ORCID: https://orcid.org/0000-0002-3920-994X)
- Hemant Kulkarni (ORCID: https://orcid.org/0000-0001-6157-2668)
- Vivien Wei-Anne Hsu
Institutions
- The University of Western Australia (AU)
- Fiona Stanley Hospital (AU)
- Pathwest Laboratory Medicine (AU)
Publication Details
- Journal
- Urology Case Reports
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1016/j.eucr.2025.103185
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00