Cystic wilms tumor, cystic partially differentiated nephroblastoma, or cystic nephroma? A case report and review of the literature

Wilms tumor, typically a solid pediatric kidney cancer, can rarely appear cystic, mimicking cystic nephroma or cystic partially differentiated nephroblastoma. We report a 20-month-old boy presented with a right abdominal mass, hypertension, and poor appetite. MRI showed a cystic renal tumor, requiring primary nephrectomy without chemotherapy. Postoperative histology revealed a cystic Wilms tumor, necessitating further treatment. This case highlights the diagnostic challenge of cystic renal tumors and emphasizes the importance of histopathology in guiding management. Surgical and chemotherapeutic strategies must be carefully individualized based on clinical and imaging findings.

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Publication Details

Journal
Urology Case Reports
Published
2025-08-31
DOI
https://doi.org/10.1016/j.eucr.2025.103186
Primary Topic
Renal and related cancers
Type
article
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article

Cystic wilms tumor, cystic partially differentiated nephroblastoma, or cystic nephroma? A case report and review of the literature

Gerhard Reinaldi Situmorang, Renaningtyas Tambun, Renandha Septaryan Yustira, Sean Peter Haruman
Urology Case Reports
Renal and related cancers
article

Cystic wilms tumor, cystic partially differentiated nephroblastoma, or cystic nephroma? A case report and review of the literature

Gerhard Reinaldi Situmorang, Renaningtyas Tambun, Renandha Septaryan Yustira, Sean Peter Haruman
article en

Abstract

Wilms tumor, typically a solid pediatric kidney cancer, can rarely appear cystic, mimicking cystic nephroma or cystic partially differentiated nephroblastoma. We report a 20-month-old boy presented with a right abdominal mass, hypertension, and poor appetite. MRI showed a cystic renal tumor, requiring primary nephrectomy without chemotherapy. Postoperative histology revealed a cystic Wilms tumor, necessitating further treatment. This case highlights the diagnostic challenge of cystic renal tumors and emphasizes the importance of histopathology in guiding management. Surgical and chemotherapeutic strategies must be carefully individualized based on clinical and imaging findings.

Urology Case ReportsVol. 63
University of Indonesia (ID), Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
Good health and well-being
Openalex Percentile: Top 80%
Renal and related cancers
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