Optimizing anisotropic margins in single‐isocenter multiple brain metastases radiosurgery using regressor strategies: A multi‐institutional validation study
While the feasibility and potential dosimetric benefits of anisotropic margins in SRS-such as improvements in the gradient index and V12-were observed, the magnitude of these differences may be modest in terms of clinical impact. The results suggest that anisotropic margins can be integrated into SRS workflows and may offer advantages in specific scenarios, particularly when minimizing brain dose is a priority.
Authors
- C Venencia (ORCID: https://orcid.org/0000-0002-8082-2957)
- Miguel Ángel Chesta
- Francisco A. Tamarit (ORCID: https://orcid.org/0000-0001-8697-2107)
- Alexis Dimitriadis (ORCID: https://orcid.org/0000-0003-4507-0734)
- José Alejandro Rojas‐López (ORCID: https://orcid.org/0000-0001-5543-3047)
- Mariana Hernández Bojórquez
- Maurizio Musso (ORCID: https://orcid.org/0009-0008-9407-1112)
- Néstor Daniel Vacca Campos (ORCID: https://orcid.org/0000-0003-1272-7509)
Institutions
- Universidad Nacional de Córdoba (AR)
- Fundación Valle del Lili (CO)
- Universidad de Puebla (MX)
- Queen Square Radiosurgery Centre (GB)
- Instituto Oncológico de Córdoba (AR)
- Centro Médico ABC (MX)
- Clínica Ruiz (MX)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1002/acm2.70249
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00