Effects of injectable platelet-rich fibrin (i-PRF) application as root surface biomodification on gingival fibroblasts: an in vitro study
The application of i-PRF for 5 min following EDTA treatment appears to enhance gingival fibroblast proliferation, attachment, and ALP expression. The effectiveness of i-PRF may vary depending on the duration of the application. Therefore, in vitro data from i-PRF followed by EDTA application to dentin surfaces may be useful for further development of in vivo and clinical approaches.
Authors
- Cenkhan Bal (ORCID: https://orcid.org/0000-0002-1205-276X)
- Cemre Altay
- Sühan Gürbüz (ORCID: https://orcid.org/0000-0003-2277-2020)
- Bülent Kurtiş
- Mustafa Güngörmüş (ORCID: https://orcid.org/0000-0001-8894-0467)
Institutions
- Sağlık Bilimleri Üniversitesi (TR)
- Ankara Yıldırım Beyazıt University (TR)
- Antalya IVF (TR)
- University of Health Sciences Antigua (AG)
- Gazi University (TR)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1186/s12903-025-06678-9
- Citations
- 1
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.84
Funders
- Gazi Üniversitesi