Clinicopathological Profile of Cutaneous Adnexal Tumors at a Tertiary Care Hospital in Pakistan

Objective: To analyze clinicopathological wise frequency of Cutaneous Adnexal Tumors presenting at a tertiary care hospital, Kharian, Pakistan. Study Design: Cross-sectional study Place and Duration of Study: Dermato-pathology department of a tertiary care hospital in Kharian, Pakistan, from Dec 2019 to Nov 2021. Methodology: The sample was collected from the biopsy specimens with clinical diagnosis indicating cutaneous tumors. Relevant clinical information was obtained from the clinical details submitted by the clinicians. The specimens were examined by a team comprising a dermatologist and a histopathologist. The Cutaneous Adnexal Tumors were classified according to the WHO classification into three groups which included Tumors with Apocrine and Eccrine, Follicular and Sebaceous differentiation. Each group was further divided into Benign and Malignant tumors. Results: A total of 41 cases with a diagnosis of Cutaneous Adnexal Tumors were encountered during the two years. These comprised 4.8% of the total number of cutaneous tumors. The mean age of patients was 39.98+15.20 years with a range of 11 years to 65 years. 53.7% of Cutaneous Adnexal Tumors were seen in the third and fourth decades of life. General surgeons submitted maximum number of biopsies (n=27, 65.8 %), followed by dermatologists (n=8, 19.5%), plastic surgeons (n=4, 9.8%), and ophthalmologists (n=2, 4.9%). 97.6% of the tumors were benign, and only one was Malignant. Tumors with Follicular Differentiation were among the most commonly presented. Pilomatrixoma was the most common Cutaneous Adnexal Tumor. 65.9% of Cutaneous Adnexal Tumors were seen on the head and neck.