Pro-Apoptosis Effects of Yangzheng-Xiaoji Capsules in Hepatocellular Carcinoma: Activation of the p53-Induced Apoptotic Pathway and Inhibition of the PI3K/Akt Pathway
The results of this study indicate that YXC exhibits anti-proliferative and pro-apoptotic pharmacological activity via activating the p53-induced apoptotic pathway and suppressing the PI3K/Akt pathway.
Authors
- Tingting Zhou (ORCID: https://orcid.org/0009-0007-3880-4935)
- Liu Li (ORCID: https://orcid.org/0000-0003-3369-3117)
- Tianhao Guo (ORCID: https://orcid.org/0000-0002-8899-2328)
- Weixing Shen (ORCID: https://orcid.org/0000-0002-6454-3296)
- Yuhan Wang (ORCID: https://orcid.org/0009-0006-8868-5316)
- Dongdong Sun (ORCID: https://orcid.org/0000-0003-1751-3884)
- Jiani Tan
- Haibo Cheng
- Chengtao Yu (ORCID: https://orcid.org/0000-0002-8427-736X)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wangjing Hospital of China Academy of Chinese Medical Sciences (CN)
- Hong Kong Metropolitan University (HK)
Publication Details
- Journal
- Integrative Cancer Therapies
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/15347354251352848
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00