Antihypertensive efficacy of allopurinol; a mini-review on current concepts

Allopurinol, primarily used to treat gout, has shown potential as an antihypertensive agent due to its effects on oxidative stress and endothelial function. This agent is not typically used as a first-line treatment for hypertension; however, some studies have suggested that it may have potential antihypertensive effects. More research is needed to establish its efficacy and mechanisms in treating hypertension.

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Publication Details

Journal
Journal of Nephropathology
Published
2025-03-15
DOI
https://doi.org/10.34172/jnp.2025.27587
Primary Topic
Natural Products and Biological Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Antihypertensive efficacy of allopurinol; a mini-review on current concepts

Omer Mansib Kassid, Hussein Ali Al‐Bahrani, Qais R. Lahhob, Ali Thoulfikar A. Imeer et al.
Journal of Nephropathology
Natural Products and Biological Research
article

Antihypertensive efficacy of allopurinol; a mini-review on current concepts

Omer Mansib Kassid, Hussein Ali Al‐Bahrani, Qais R. Lahhob, Ali Thoulfikar A. Imeer, Abdul Amir H. Kadhum, Maytham Ahmed AbdulAemah
article en

Abstract

Allopurinol, primarily used to treat gout, has shown potential as an antihypertensive agent due to its effects on oxidative stress and endothelial function. This agent is not typically used as a first-line treatment for hypertension; however, some studies have suggested that it may have potential antihypertensive effects. More research is needed to establish its efficacy and mechanisms in treating hypertension.

Journal of NephropathologyVol. 14
University of Babylon (IQ), Thi Qar University (IQ), University of Misan (IQ), University of Kerbala (IQ)
Openalex Percentile: Top 63%
Natural Products and Biological Research
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