Tropomyosin isoforms encoded by TPM2 control the actin-bundling activity of fascin-1
Cytoplasmic Tpm2 isoforms regulate actin bundling activity of fascin-1 by organizing protein composition in the bundles, a mechanism that may contribute to the suppression of metastatic phenotype in cancer cells.
Authors
- Katarzyna Robaszkiewicz (ORCID: https://orcid.org/0000-0001-6050-8437)
- Gábor Talián
- Petr Beneš (ORCID: https://orcid.org/0000-0002-8297-9675)
- Lucia Knopfová (ORCID: https://orcid.org/0000-0003-4897-0404)
- Joanna Moraczewska (ORCID: https://orcid.org/0000-0003-4518-3843)
- Jiří Navrátil (ORCID: https://orcid.org/0000-0001-6717-1259)
- Małgorzata Siatkowska (ORCID: https://orcid.org/0000-0003-0548-0368)
- Andrea Rousová
Institutions
- Kazimierz Wielki University in Bydgoszcz (PL)
- Masaryk University (CZ)
- University Hospital Brno (CZ)
- St. Anne's University Hospital Brno (CZ)
- University of Pecs (HU)
Publication Details
- Journal
- Biological Research
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1186/s40659-025-00640-3
- Citations
- 2
- Primary Topic
- Cellular Mechanics and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 2.30
Funders
- European Commission
- Ministerstvo Školství, Mládeže a Tělovýchovy
- Grantová Agentura České Republiky
- Narodowe Centrum Nauki
- Narodowym Centrum Nauki
- Centre National de la Recherche Scientifique
- Pécsi Tudományegyetem