Ketamine infusion therapy in an elderly patient with complex regional pain syndrome and major depression

Complex regional pain syndrome (CRPS) is a chronic pain disorder that severely affects mobility and quality of life. This case report describes an 86-year-old man who has a long-standing history of CRPS-related back and leg pain. Traditional treatments, including opioids and duloxetine, did not improve his symptoms, and due to religious beliefs restricting specific interventions, standard hospital care was limited. Given the severity of his symptoms and the refractory nature of his condition, an intravenous ketamine infusion was recommended to improve pain and comorbid depressive symptoms. Following one treatment, the patient exhibited immediate and substantial improvements in pain intensity, mood, and mobility. This case accentuates the importance of culturally sensitive, patient-centered care and suggests the role of ketamine in treating CRPS when traditional therapies are ineffective.

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Publication Details

Journal
International Journal of Community Medicine and Public Health
Published
2025-08-30
DOI
https://doi.org/10.18203/2394-6040.ijcmph20252868
Primary Topic
Pain Management and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Ketamine infusion therapy in an elderly patient with complex regional pain syndrome and major depression

Aatish D. Bhatta, Parinda Parikh, Anuj Kumar Shukla, Shaurya K. Singh et al.
International Journal of Community Medicine and Public Health
Pain Management and Treatment
article

Ketamine infusion therapy in an elderly patient with complex regional pain syndrome and major depression

Aatish D. Bhatta, Parinda Parikh, Anuj Kumar Shukla, Shaurya K. Singh, Ashish Chandra, Mahiya Buddhavarapu, Alisha Arul Alphonse, Mina Oza, Himani J Suthar, Jeremy Kays, Parthiv Pansuriya, Zoe Gellert
article en

Abstract

Complex regional pain syndrome (CRPS) is a chronic pain disorder that severely affects mobility and quality of life. This case report describes an 86-year-old man who has a long-standing history of CRPS-related back and leg pain. Traditional treatments, including opioids and duloxetine, did not improve his symptoms, and due to religious beliefs restricting specific interventions, standard hospital care was limited. Given the severity of his symptoms and the refractory nature of his condition, an intravenous ketamine infusion was recommended to improve pain and comorbid depressive symptoms. Following one treatment, the patient exhibited immediate and substantial improvements in pain intensity, mood, and mobility. This case accentuates the importance of culturally sensitive, patient-centered care and suggests the role of ketamine in treating CRPS when traditional therapies are ineffective.

International Journal of Community Medicine and Public HealthVol. 12(9)
Tulane University (US), St. George's University (GD), Gandhi Medical College & Hospital (IN), University of Pittsburgh (US), Cornell University (US), Windsor University School of Medicine (KN), Pravara Institute of Medical Sciences (IN), St. Martinus University (CW), Tula University (RU), Government Medical College (IN), Burke Medical Research Institute (US), National Health Promotion Associates (US), KIST Medical College (NP), New York University (US)
Openalex Percentile: Top 64%
Pain Management and Treatment
DOIOpen Access PDFOpenAlex
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