<b>Histopathological study of the neuroprotective effects of Gum Arabic and Fenchol on neuronal cells in an Alzheimer’s disease rat model</b>

The findings suggested that Gum Arabic and Fenchol possess neuroprotective properties, suggesting their potential as therapeutic agents for AD, with efficacy comparable to that of memantine. Their ability to downregulate IL-6 further highlights their potential in mitigating neuroinflammation associated with Alzheimer's pathology. Further investigations are warranted to elucidate their underlying mechanisms and evaluate their potential clinical applications.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i8.53
Primary Topic
Polysaccharides Composition and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Histopathological study of the neuroprotective effects of Gum Arabic and Fenchol on neuronal cells in an Alzheimer’s disease rat model

Layla Alhasan, Fadhil Abbas Khudhair Al Ghaliby
Open Veterinary Journal
Polysaccharides Composition and Applications
article

Histopathological study of the neuroprotective effects of Gum Arabic and Fenchol on neuronal cells in an Alzheimer’s disease rat model

Layla Alhasan, Fadhil Abbas Khudhair Al Ghaliby
article en

Abstract

The findings suggested that Gum Arabic and Fenchol possess neuroprotective properties, suggesting their potential as therapeutic agents for AD, with efficacy comparable to that of memantine. Their ability to downregulate IL-6 further highlights their potential in mitigating neuroinflammation associated with Alzheimer's pathology. Further investigations are warranted to elucidate their underlying mechanisms and evaluate their potential clinical applications.

Open Veterinary JournalVol. 15(8)
Thi Qar University (IQ), Iraqi University (IQ)
Foundation for Food and Agriculture Research, University of Thi-Qar
Openalex Percentile: Top 73%
Polysaccharides Composition and Applications
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