High variation in purity of consumer-level illicit fentanyl samples in Los Angeles, September 2023–April 2025

We found high variation in IMF purity among samples sold as fentanyl, even among samples obtained on the same day, in the same location. This volatility likely plays a role in high overdose risk, even among people with opioid tolerance, in the fentanyl era. Further research is needed to compare these findings to other locations across the United States.

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Publication Details

Journal
International Journal of Drug Policy
Published
2025-08-30
DOI
https://doi.org/10.1016/j.drugpo.2025.104977
Citations
5
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
9.39
Controls
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article

High variation in purity of consumer-level illicit fentanyl samples in Los Angeles, September 2023–April 2025

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International Journal of Drug Policy
Opioid Use Disorder Treatment
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article

High variation in purity of consumer-level illicit fentanyl samples in Los Angeles, September 2023–April 2025

Ruby Romero, Michelle Poimboeuf, Chelsea L. Shover, Joseph Friedman, Morgan Godvin, Caitlin A. Molina, Bryce Pardo, David Goodman‐Meza, Adam J Koncsol, Jasmine Feng
article en
5 citations

Abstract

We found high variation in IMF purity among samples sold as fentanyl, even among samples obtained on the same day, in the same location. This volatility likely plays a role in high overdose risk, even among people with opioid tolerance, in the fentanyl era. Further research is needed to compare these findings to other locations across the United States.

International Journal of Drug PolicyVol. 145
Los Angeles County Department of Health Services (US), UCLA Health (US), UNSW Sydney (AU), United Nations Office on Drugs and Crime (AT), University of California San Diego (US)
Zero hunger
Openalex Percentile: Top 2%
Opioid Use Disorder Treatment
9.39
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