Pyoderma Gangrenosum as a Presenting Symptom of Inflammatory Bowel Disease

Pyoderma gangrenosum (PG) is a rare ulcerative dermatosis, with over half of cases associated with a systemic inflammatory condition. PG is a rare condition, and its diagnosis often proves elusive as its clinical and histopathologic findings are nonspecific; indeed, it is considered a diagnosis of exclusion. We present a case of PG as the presenting symptom of a patient's previously undiagnosed inflammatory bowel disease, highlighting the necessity of initiating a broad work-up for associated systemic inflammatory conditions when a diagnosis of PG is suspected or confirmed.

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Publication Details

Journal
Cureus
Published
2025-08-30
DOI
https://doi.org/10.7759/cureus.91303
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Pyoderma Gangrenosum as a Presenting Symptom of Inflammatory Bowel Disease

D Li, G. Peter Sarantopoulos, Jaime Cok García, Tyler R Jarrett
1 links
Cureus
Autoimmune and Inflammatory Disorders
article

Pyoderma Gangrenosum as a Presenting Symptom of Inflammatory Bowel Disease

D Li, G. Peter Sarantopoulos, Jaime Cok García, Tyler R Jarrett
article en

Abstract

Pyoderma gangrenosum (PG) is a rare ulcerative dermatosis, with over half of cases associated with a systemic inflammatory condition. PG is a rare condition, and its diagnosis often proves elusive as its clinical and histopathologic findings are nonspecific; indeed, it is considered a diagnosis of exclusion. We present a case of PG as the presenting symptom of a patient's previously undiagnosed inflammatory bowel disease, highlighting the necessity of initiating a broad work-up for associated systemic inflammatory conditions when a diagnosis of PG is suspected or confirmed.

CureusVol. 17(8)
University of California, Los Angeles (US)
Good health and well-being
Openalex Percentile: Top 69%
Autoimmune and Inflammatory Disorders
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