Association between plasma phosphate/pyrophosphate ratio and computed tomography–derived aortic valve calcification score in an unselected cohort of cardiovascular patients
This is the first study to investigate the association between PPi homeostasis and AVC in humans. The plasma Pi/PPi ratio was significantly positively associated with the AVC load even after adjustment for traditional risk factors.
Authors
- Flóra Szeri (ORCID: https://orcid.org/0000-0003-2572-6820)
- Anikó Ilona Nagy (ORCID: https://orcid.org/0000-0002-0519-5172)
- Astrid Apor (ORCID: https://orcid.org/0000-0002-9132-0979)
- Ádám L. Jermendy (ORCID: https://orcid.org/0000-0001-8295-0840)
- Márton Rakovics (ORCID: https://orcid.org/0000-0002-5830-4870)
- Bálint Szilveszter (ORCID: https://orcid.org/0000-0003-1530-4288)
- Tamás Arányi (ORCID: https://orcid.org/0000-0002-2087-6275)
- Dávid Szüts (ORCID: https://orcid.org/0000-0001-7985-0136)
- Magnus Bäck (ORCID: https://orcid.org/0000-0003-0853-5141)
- E Straub
- Aristomenis Manouras (ORCID: https://orcid.org/0000-0002-6617-2070)
- Béla Péter Merkely (ORCID: https://orcid.org/0000-0001-6514-0723)
- Edit Dósa (ORCID: https://orcid.org/0000-0003-2984-2642)
- Dénes Juhász
- Martin Várhegyi
Institutions
- Semmelweis University (HU)
- Eötvös Loránd University (HU)
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Défaillance Cardiovasculaire Aiguë et Chronique
- HUN-REN Research Centre for Natural Sciences (HU)
- Université de Lorraine (FR)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Imaging
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1093/ehjci/jeaf247
- Citations
- 4
- Primary Topic
- Aortic Thrombus and Embolism
- Type
- article
- Field-Weighted Citation Impact
- 6.07
Funders
- Fonds Wetenschappelijk Onderzoek
- Magyar Tudományos Akadémia
- Vetenskapsrådet
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
- Vlaamse regering