A Rare Variant of Ameloblastoma Emulating as a Gingival Overgrowth: A Report of Two Cases

Peripheral ameloblastoma is a rare, benign odontogenic tumor that arises in the soft tissues of the oral mucosa. We present two cases of peripheral ameloblastoma located on the mandibular alveolar ridge, each manifesting as a painless, firm, exophytic mass initially suspected to be a reactive granulomatous lesion. Notably, the first case occurred in a patient with a prior history of intraosseous ameloblastoma in the same region, which makes this presentation clinically significant and raises important considerations regarding tumor pathogenesis and potential recurrence. Histopathological examination confirmed the diagnosis of peripheral ameloblastoma. Wide local excision was performed as the treatment of choice in both cases. The report of these cases highlights the importance of including odontogenic tumors in the differential diagnosis of persistent gingival overgrowth and highlights the need for histopathological evaluation to ensure accurate diagnosis and management.

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Publication Details

Journal
Cureus
Published
2025-08-30
DOI
https://doi.org/10.7759/cureus.91298
Primary Topic
Oral and Maxillofacial Pathology
Type
article
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0.00
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article

A Rare Variant of Ameloblastoma Emulating as a Gingival Overgrowth: A Report of Two Cases

A Roshni, Tom Thomas, S. Arjun, Sudhamshu K.C. et al.
Cureus
Oral and Maxillofacial Pathology
article

A Rare Variant of Ameloblastoma Emulating as a Gingival Overgrowth: A Report of Two Cases

A Roshni, Tom Thomas, S. Arjun, Sudhamshu K.C., R Ananthu
article en

Abstract

Peripheral ameloblastoma is a rare, benign odontogenic tumor that arises in the soft tissues of the oral mucosa. We present two cases of peripheral ameloblastoma located on the mandibular alveolar ridge, each manifesting as a painless, firm, exophytic mass initially suspected to be a reactive granulomatous lesion. Notably, the first case occurred in a patient with a prior history of intraosseous ameloblastoma in the same region, which makes this presentation clinically significant and raises important considerations regarding tumor pathogenesis and potential recurrence. Histopathological examination confirmed the diagnosis of peripheral ameloblastoma. Wide local excision was performed as the treatment of choice in both cases. The report of these cases highlights the importance of including odontogenic tumors in the differential diagnosis of persistent gingival overgrowth and highlights the need for histopathological evaluation to ensure accurate diagnosis and management.

CureusVol. 17(8)
Manubhai Patel Dental College and Hospital (IN)
Zero hunger
Openalex Percentile: Top 68%
Oral and Maxillofacial Pathology
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