Intramolecular Azide–Alkene Cycloaddition—The Logothetis Reaction
The assembly of cyclic amines is fundamental to medicinal chemistry. While intramolecular azide – alkyne cycloaddition is widely practiced, intramolecular azide – alkene cycloaddition is much less used, even though it has been known since 1965. This review is an overview of the applications of intramolecular azide – alkene cycloaddition in target‐directed synthesis since that time.
Authors
- Douglass F. Taber (ORCID: https://orcid.org/0000-0003-2287-5759)
Institutions
- University of Delaware (US)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1002/ejoc.202500472
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00