Pharmacokinetic-pharmacodynamic and tissue distribution studies in physiological and cerebral ischemia-reperfusion injury rats after oral administration of anisodine hydrobromide tablets
The study demonstrated that AH could be rapidly and extensively distributed to various tissues in rats. AH is a promising drug for the treatment of rat models of CIRI.
Authors
- Shu Dai (ORCID: https://orcid.org/0000-0001-6115-3527)
- Yanfang Liu (ORCID: https://orcid.org/0000-0002-3442-259X)
- Nan Feng (ORCID: https://orcid.org/0000-0002-1812-754X)
- Jianlan Zhang (ORCID: https://orcid.org/0000-0003-3106-6806)
- Chenhao Yao (ORCID: https://orcid.org/0009-0001-0159-2568)
- Yuxin Yao (ORCID: https://orcid.org/0000-0002-9358-7730)
- Rui Wu (ORCID: https://orcid.org/0000-0001-6134-5393)
- Yunxia Li (ORCID: https://orcid.org/0000-0002-9256-5716)
- Feng Wan (ORCID: https://orcid.org/0000-0002-8110-3460)
- Yujie Yu
Institutions
- Mochida Pharmaceutical (Japan) (JP)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1080/17576180.2025.2554567
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Natural Science Foundation of China
- Sichuan Province Science and Technology Support Program