Outcome of systemic therapy in patients with advanced rare skin cancers: A retrospective multicenter DeCOG study of 209 patients
Type and outcome of systemic therapy differed between cancer entities. Efficacy of ICI was high in PDS and AS, moderate in KS, and low in CAC. Patients with advanced CAC revealed an extremely poor prognosis regardless of the type of therapy used.
Authors
- Robin Reschke (ORCID: https://orcid.org/0000-0002-2850-2526)
- Carsten Weishaupt (ORCID: https://orcid.org/0000-0003-1195-2106)
- Berenice M. Lang (ORCID: https://orcid.org/0000-0002-4679-3777)
- Patrick Terheyden (ORCID: https://orcid.org/0000-0002-5894-1677)
- Jochen Sven Utikal (ORCID: https://orcid.org/0000-0001-5316-0241)
- Bastian Schilling (ORCID: https://orcid.org/0000-0001-8859-4103)
- Michael Erdmann (ORCID: https://orcid.org/0000-0001-7136-6489)
- Edgar Dippel (ORCID: https://orcid.org/0000-0002-4433-2387)
- Ralf Gutzmer (ORCID: https://orcid.org/0000-0001-7921-2820)
- Christoffer Gebhardt (ORCID: https://orcid.org/0000-0001-7090-9584)
- Cindy Franklin (ORCID: https://orcid.org/0000-0001-9142-5423)
- Michael Weichenthal (ORCID: https://orcid.org/0000-0002-9060-4961)
- Sebastian Haferkamp (ORCID: https://orcid.org/0000-0002-3894-8345)
- Katharina C. Kähler (ORCID: https://orcid.org/0000-0001-9953-0893)
- Dirk Schadendorf (ORCID: https://orcid.org/0000-0003-3524-7858)
- Christoph Pöttgen (ORCID: https://orcid.org/0000-0002-9224-9318)
- Miriam Mengoni (ORCID: https://orcid.org/0000-0002-1651-7114)
- Peter Mohr (ORCID: https://orcid.org/0000-0002-7328-7407)
- Georg Christian Lodde (ORCID: https://orcid.org/0000-0002-6930-2694)
- Julia Welzel (ORCID: https://orcid.org/0000-0002-6099-7418)
- Alpaslan Tasdogan (ORCID: https://orcid.org/0000-0003-2543-852X)
- Martin Gschnell
- Thilo Gambichler (ORCID: https://orcid.org/0000-0001-7862-3695)
- Teresa Amaral (ORCID: https://orcid.org/0000-0002-2516-5181)
- Doris Helbig (ORCID: https://orcid.org/0000-0002-5841-4631)
- Selma Ugurel (ORCID: https://orcid.org/0000-0002-9384-6704)
- Jürgen Christian Becker (ORCID: https://orcid.org/0000-0001-9183-653X)
- Jessica Cecile Hassel (ORCID: https://orcid.org/0000-0001-7575-6230)
- Gaston Schley
- P. Dücker
- Ulrike Raap (ORCID: https://orcid.org/0000-0002-9573-4714)
- Lydia Reinhardt (ORCID: https://orcid.org/0000-0001-6232-5132)
- Gabriela Poch (ORCID: https://orcid.org/0000-0003-3948-2505)
- Thomas Tüting (ORCID: https://orcid.org/0000-0001-7146-0934)
- Alexander Kreuter (ORCID: https://orcid.org/0000-0003-2275-499X)
- Ulrike Leiter (ORCID: https://orcid.org/0000-0002-8019-1577)
- Nessr Abu Rached (ORCID: https://orcid.org/0000-0001-6853-0743)
- Michael Sachse
- Lena Nanz
- Lucie Heinzerling
- Kai-Martin Thoms
- Jan-Malte Placke
- Franziska Jochims
Institutions
- Goethe University Frankfurt (DE)
- Universität Hamburg (DE)
- Philipps University of Marburg (DE)
- University of Applied Sciences Mainz (DE)
- German Cancer Research Center (DE)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- Universitätsklinikum Gießen und Marburg (DE)
- University Hospital Augsburg (DE)
- University Hospital Heidelberg (DE)
- University Hospital Regensburg (DE)
- Humboldt-Universität zu Berlin (DE)
- Universitätsklinikum Erlangen (DE)
- Düsseldorf University Hospital (DE)
- Universitäres Kinderwunschzentrum Lübeck (DE)
- Helios Hospital Schwerin (DE)
- University Hospital Münster (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Klinikum Oldenburg (DE)
- National Center for Tumor Diseases (DE)
- University Hospital Schleswig-Holstein (DE)
- Essen University Hospital (DE)
- HELIOS St. Elisabeth Klinik Oberhausen (DE)
- University Children's Hospital Tübingen (DE)
- University Hospital Leipzig (DE)
- Universitätsklinikum Würzburg (DE)
- Klinikum Dortmund (DE)
- Klinikum Ludwigshafen (DE)
- Klinikum Bielefeld (DE)
- University Hospital Frankfurt (DE)
- University Hospital Magdeburg (DE)
- Elbe Kliniken Stade-Buxtehude (DE)
- Helios Kliniken (DE)
- Klinikum Bremerhaven-Reinkenheide (DE)
- University Hospital Cologne (DE)
- West German Heart and Vascular Center Essen (DE)
- University Hospital Carl Gustav Carus (DE)
- Johannes Wesling Klinikum Minden (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Duisburg-Essen (DE)
- University of Göttingen (DE)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
- Ruhr University Bochum (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1016/j.ejca.2025.115750
- Citations
- 1
- Primary Topic
- Vascular Tumors and Angiosarcomas
- Type
- article
- Field-Weighted Citation Impact
- 1.05