Malignant Brenner tumor with extensive clear cell features: A valuable diagnostic lesson learned from molecular tumor profiling and AI-based tumor differential tool

MBT should be considered in the differential diagnosis of ovarian neoplasms with clear cell features. Extensive tumor sampling combined with careful evaluation of the histologic and immunohistochemical features and molecular analysis is the key to accurate diagnosis. AI-based tumor differential tools are valuable adjuncts to tumor diagnostics when investigated with other pathological and clinical findings.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2025-08-29
DOI
https://doi.org/10.1016/j.gore.2025.101939
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Malignant Brenner tumor with extensive clear cell features: A valuable diagnostic lesson learned from molecular tumor profiling and AI-based tumor differential tool

Marzia Capelletti, Apsra Nasir, Yun-An Tseng, Hassan Ghani et al.
Gynecologic Oncology Reports
Ovarian cancer diagnosis and treatment
article

Malignant Brenner tumor with extensive clear cell features: A valuable diagnostic lesson learned from molecular tumor profiling and AI-based tumor differential tool

Marzia Capelletti, Apsra Nasir, Yun-An Tseng, Hassan Ghani, M. Ruhul Quddus, Ashley Stuckey, Corinne Jansen
article en

Abstract

MBT should be considered in the differential diagnosis of ovarian neoplasms with clear cell features. Extensive tumor sampling combined with careful evaluation of the histologic and immunohistochemical features and molecular analysis is the key to accurate diagnosis. AI-based tumor differential tools are valuable adjuncts to tumor diagnostics when investigated with other pathological and clinical findings.

Gynecologic Oncology ReportsVol. 61
Brown University (US), Women & Infants Hospital of Rhode Island (US), Caris Life Sciences (United States) (US)
Openalex Percentile: Top 70%
Ovarian cancer diagnosis and treatment
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