Malignant Brenner tumor with extensive clear cell features: A valuable diagnostic lesson learned from molecular tumor profiling and AI-based tumor differential tool
MBT should be considered in the differential diagnosis of ovarian neoplasms with clear cell features. Extensive tumor sampling combined with careful evaluation of the histologic and immunohistochemical features and molecular analysis is the key to accurate diagnosis. AI-based tumor differential tools are valuable adjuncts to tumor diagnostics when investigated with other pathological and clinical findings.
Authors
- Marzia Capelletti (ORCID: https://orcid.org/0000-0001-5095-7060)
- Apsra Nasir (ORCID: https://orcid.org/0000-0003-3644-911X)
- Yun-An Tseng
- Hassan Ghani
- M. Ruhul Quddus (ORCID: https://orcid.org/0000-0002-1371-9095)
- Ashley Stuckey
- Corinne Jansen
Institutions
- Brown University (US)
- Women & Infants Hospital of Rhode Island (US)
- Caris Life Sciences (United States) (US)
Publication Details
- Journal
- Gynecologic Oncology Reports
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1016/j.gore.2025.101939
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00