International consensuses and guidelines on etiology, diagnosis, treatment, and future developments of neovascular age-related macular degeneration (nAMD) by the Asia-Pacific Vitreo-retina Society (APVRS), the Asia-Pacific Ocular Imaging Society (APO
Neovascular age-related degeneration (nAMD) is one of the leading causes of visual impairment in older populations in the developed world. With the aging population, the incidence of nAMD is growing globally. Despite advancements in diagnostic investigations and treatment modalities over the past three decades, there remains considerable controversies in the pathogenesis, classification and optimal management strategies. An international panel of 31 experts from 11 countries/regions prepared and voted on consensus statements in five key areas: (1) etiology controversies; (2) diagnosis controversies; (3) treatment controversies; (4) future development controversies; and (5) healthcare deliveries controversies. Among the 31 consensus statements, 28 (90.3 %) have achieved over 75 % agreement. These statements can provide a practical guide for ophthalmologists to provide the optimal care of patients with nAMD and for planning future research priorities in order to address the unmet needs in nAMD.
Authors
- Youxin Chen (ORCID: https://orcid.org/0000-0002-7231-5058)
- Danny Siu‐Chun Ng (ORCID: https://orcid.org/0000-0001-6566-1019)
- Dennis S.C. Lam (ORCID: https://orcid.org/0000-0001-5276-3702)
- Timothy Y. Y. Lai (ORCID: https://orcid.org/0000-0002-7832-6428)
- Li Jia Chen (ORCID: https://orcid.org/0000-0003-3500-5840)
- Andrew Chang (ORCID: https://orcid.org/0000-0001-7555-1585)
- Fumi Gomi (ORCID: https://orcid.org/0000-0003-0807-8817)
- Susan S. Huang (ORCID: https://orcid.org/0000-0001-6748-3447)
- Robyn H. Guymer (ORCID: https://orcid.org/0000-0002-9441-4356)
- Tommy Kwan Hin Fong (ORCID: https://orcid.org/0000-0002-3674-7080)
- Muna Bhende (ORCID: https://orcid.org/0000-0002-9251-170X)
- Mahesh Shanmugam (ORCID: https://orcid.org/0000-0002-1912-4412)
- Mariko Sasaki (ORCID: https://orcid.org/0000-0001-5608-0546)
- Sobha Sivaprasad (ORCID: https://orcid.org/0000-0001-8952-0659)
- Xinyuan Zhang (ORCID: https://orcid.org/0000-0002-3372-0798)
- Tien Yin Wong (ORCID: https://orcid.org/0000-0002-8448-1264)
- Jay Kumar Chhablani (ORCID: https://orcid.org/0000-0003-1772-3558)
- Yi‐Ting Hsieh (ORCID: https://orcid.org/0000-0003-2258-154X)
- Keiko Kataoka (ORCID: https://orcid.org/0000-0002-8795-6536)
- Chui Ming Gemmy Cheung (ORCID: https://orcid.org/0000-0003-3358-3516)
- Annabelle A. Okada (ORCID: https://orcid.org/0000-0002-8850-8962)
- Rajendra S. Apte (ORCID: https://orcid.org/0000-0003-2281-2336)
- Judy E. Kim (ORCID: https://orcid.org/0000-0001-8695-4363)
- Gregg T. Kokame (ORCID: https://orcid.org/0000-0001-7487-2205)
- Xiaoxin Li (ORCID: https://orcid.org/0000-0002-8645-4331)
- Adrian Koh
- Srinivas R. Sadda
- Lalit Verma
- Nishant Radke
- Voraporn Chiakitmongkol
Institutions
- Sankara Nethralaya (IN)
- Beijing Tongren Hospital (CN)
- The University of Sydney (AU)
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- University of Hawaii System (US)
- Tokyo Medical University (JP)
- University of Pittsburgh (US)
- Chinese University of Hong Kong (HK)
- Kyorin University (JP)
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Keio University (JP)
- Washington University in St. Louis (US)
- Singapore National Eye Center (SG)
- Hong Kong Eye Hospital (CN)
- Peking Union Medical College Hospital (CN)
- Sydney Hospital (AU)
- National Institute for Health and Care Research (GB)
- University of Illinois Chicago (US)
- Doheny Eye Institute (US)
- Centre for Eye Research Australia (AU)
- Eye & Retina Surgeons (SG)
- Singapore Eye Research Institute (SG)
- Chinese University of Hong Kong, Shenzhen (CN)
- National Taiwan University Hospital (TW)
- Shenzhen Luohu People's Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Eye Hospital in Bangalore (IN)
- Centre for Sight (IN)
- University College London (GB)
- Chiang Mai University (TH)
- Hyogo University (JP)
- The University of Texas Southwestern Medical Center (US)
- Tsinghua University (CN)
Publication Details
- Journal
- Asia-Pacific Journal of Ophthalmology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1016/j.apjo.2025.100242
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00