Clonal Hematopoiesis and Risk of New-Onset Myocarditis and Pericarditis
In this study, CHIP was a strong risk factor for myocarditis and pericarditis among middle-aged adults. Targeting CHIP and its downstream pathways may represent a strategy for preventing or treating pericarditis and myocarditis.
Authors
- Md Mesbah Uddin (ORCID: https://orcid.org/0000-0003-1846-0411)
- Spencer Flynn (ORCID: https://orcid.org/0000-0001-5854-3751)
- Michael C. Honigberg (ORCID: https://orcid.org/0000-0001-8630-5021)
- Nathalie Conrad (ORCID: https://orcid.org/0000-0001-5027-5481)
- Art Schuermans (ORCID: https://orcid.org/0000-0001-8146-9692)
- Abhishek Niroula (ORCID: https://orcid.org/0000-0002-5904-0635)
- Peter Sinnaeve (ORCID: https://orcid.org/0000-0003-4716-5892)
- Peter Libby (ORCID: https://orcid.org/0000-0002-1502-502X)
- Pradeep Natarajan (ORCID: https://orcid.org/0000-0001-8402-7435)
- Amy E. Lin (ORCID: https://orcid.org/0000-0002-0554-2832)
- Brittany Weber (ORCID: https://orcid.org/0000-0002-0177-2091)
- Benjamin L. Ebert (ORCID: https://orcid.org/0000-0003-0197-5451)
- Werner Budts (ORCID: https://orcid.org/0000-0001-5850-5413)
Institutions
- Broad Institute (US)
- Brigham and Women's Hospital (US)
- University of California, San Francisco (US)
- Science for Life Laboratory (SE)
- University of Oxford (GB)
- Massachusetts General Hospital (US)
- Dana-Farber Cancer Institute (US)
- Mass General Brigham (US)
- University of Gothenburg (SE)
- KU Leuven (BE)
Publication Details
- Journal
- JAMA Cardiology
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1001/jamacardio.2025.3369
- Citations
- 11
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 19.47