An MRI-based model for preoperative prediction of tertiary lymphoid structures in patients with gallbladder cancer
This combined model is useful for predicting response and prognosis, not only for the recurrence-free survival of patients with GBC who have undergone surgery, but also for the overall survival of patients who have received immunotherapy KEY POINTS: Intratumoural TLSs independently predict recurrence-free survival of GBC. Our MRI-based combined model is a preoperative TLS marker. The combined model accurately stratifies postoperative/post-immunotherapy recurrence-free and overall survival of GBC.
Authors
- Jianming Ying (ORCID: https://orcid.org/0000-0003-2692-4052)
- Jingzhong Ouyang (ORCID: https://orcid.org/0000-0002-3398-6465)
- Yanzhao Zhou (ORCID: https://orcid.org/0000-0001-6612-5648)
- Xinming Zhao (ORCID: https://orcid.org/0000-0001-7286-771X)
- Zeliang Ma (ORCID: https://orcid.org/0000-0001-8250-0540)
- Jinxue Zhou (ORCID: https://orcid.org/0000-0002-1168-1396)
- Lizhi Xie (ORCID: https://orcid.org/0000-0002-4379-9348)
- Yi Yang (ORCID: https://orcid.org/0000-0002-9835-4098)
- Zhuo Li (ORCID: https://orcid.org/0000-0001-7775-2831)
- Feng Ye (ORCID: https://orcid.org/0000-0002-4210-3345)
- Sicong Wang (ORCID: https://orcid.org/0009-0009-6779-5112)
- Ying Xü (ORCID: https://orcid.org/0000-0002-9190-6515)
- Weihua Zhi
Institutions
- University of Electronic Science and Technology of China (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Zhengzhou University (CN)
- National Cancer Center (US)
- National Clinical Research Center for Digestive Diseases (CN)
- United Imaging Healthcare (China) (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1186/s13244-025-02007-4
- Citations
- 1
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Chinese Society of Clinical Oncology