Extreme variability in linezolid concentrations in the ICU: A case for routine therapeutic drug monitoring
Routine TDM is essential to optimize the safely and effectively manage linezolid therapy in ICU patients. This case underscores the importance of integrating TDM with PK modeling to guide personalized dosing strategies in complex and dynamic clinical scenarios.
Authors
- M. Ramos Alvarez
- Lorenzo Villa Zapata (ORCID: https://orcid.org/0000-0002-3821-4595)
- Daniel López Muñoz (ORCID: https://orcid.org/0000-0002-8667-8159)
- Derek Hales (ORCID: https://orcid.org/0000-0001-5014-3892)
Institutions
- University of Georgia (US)
- San Sebastián University (CL)
Publication Details
- Journal
- American Journal of Health-System Pharmacy
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1093/ajhp/zxaf235
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00