Cardiovascular-Focused Messaging to Improve Influenza Vaccination Rates

In a large individually randomized trial embedded in routine care across a national U.S. health system, a cardiovascular-focused nudge intervention did not increase influenza vaccination rates on a background of low uptake. Nevertheless, this trial illustrates the feasibility of conducting large care-embedded trials of nudges in U.S. health systems. (Funded by Kaiser Permanente's Garfield Memorial Fund; trial registration, ClinicalTrials.gov NCT06571747.).

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Publication Details

Journal
NEJM Evidence
Published
2025-08-30
DOI
https://doi.org/10.1056/evidoa2500208
Citations
6
Primary Topic
Influenza Virus Research Studies
Type
article
Field-Weighted Citation Impact
8.13
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article

Cardiovascular-Focused Messaging to Improve Influenza Vaccination Rates

Thida C. Tan, Ben J. Marafino, Natalia Berry, Brian Lee Claggett et al.
6 citations
NEJM Evidence
Influenza Virus Research Studies
8.13
article

Cardiovascular-Focused Messaging to Improve Influenza Vaccination Rates

Thida C. Tan, Ben J. Marafino, Natalia Berry, Brian Lee Claggett, Deepak L. Bhatt, Andrew P. Ambrosy, Alan S. Go, Svasti Patel, Mark E. Mummert, Benjamin Z. Galper, K Lee, Muthiah Vaduganathan, Rishi Parikh, Niklas Dyrby Johansen, Tor Biering‐Sørensen, Ivy Ku, Ann Jones, Scott D Solomon, Rebecca Fitch, Haihong Hu, Zoe Ballance, Gerardo Hernandez-Diaz
article en
6 citations

Abstract

In a large individually randomized trial embedded in routine care across a national U.S. health system, a cardiovascular-focused nudge intervention did not increase influenza vaccination rates on a background of low uptake. Nevertheless, this trial illustrates the feasibility of conducting large care-embedded trials of nudges in U.S. health systems. (Funded by Kaiser Permanente's Garfield Memorial Fund; trial registration, ClinicalTrials.gov NCT06571747.).

NEJM EvidenceVol. 4(10)
Dartmouth College (US), University of Copenhagen (DK), Brigham and Women's Hospital (US), Kaiser Permanente (US), Harvard University (US), Palo Alto University (US), University of California, San Francisco (US), Gentofte Hospital (DK), Colorado Permanente Medical Group (US), Stanford University (US)
Openalex Percentile: Top 2%
Influenza Virus Research Studies
8.13
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