Preparation and Characterization of <i>Persea Americana</i> Silver Nanoparticles

The global impact of Peptic Ulcer Disease poses significant health challenges, with the costs and side effects of conventional medications often outweighing their benefits; this has led to failure in therapy or inefficacy of drug therapy. Phytomedicines are being investigated for their potential in the treatment of peptic ulcer disease. Silver nanoparticles (AgNPs) have unique properties that make them suitable for diverse therapies, and green synthesis of AgNPs is gaining popularity due to its cost-effectiveness and energy efficiency. In this study, Silver (Ag) nanoparticles (NPs) were effectively synthesized by a green synthesis method using <i>Persea americana</i> aqueous leaf extract. Characterization was performed using UV-visible spectroscopy and Zeta sizer. The colour change from light brown to dark brown confirmed AgNP formation, with maximum absorption peaks at 340 nm in UV-visible spectroscopy. The average particle size of optimized batch was 70.37 nm. The study highlights the potential of green synthesis via nanoparticle technology to improve the therapeutic effectiveness of natural remedies for peptic ulcer, presenting a promising avenue for the development of more efficient and safer medicines.