Systematic analysis identifies CDKN2A as a prognostic biomarker for hepatocellular carcinoma
This study demonstrates that CDKN2A is significantly overexpressed in HCC and plays a role in immune microenvironment modulation. CDKN2A serves as a promising independent prognostic biomarker for HCC, associated with poorer patient survival.
Authors
- Xiao Liang (ORCID: https://orcid.org/0000-0002-9423-9201)
- Shilin He (ORCID: https://orcid.org/0000-0002-8595-5388)
- Junjie Xu (ORCID: https://orcid.org/0000-0001-6507-6442)
- Yanling Zhang (ORCID: https://orcid.org/0000-0001-6381-1765)
Institutions
- National Instruments (Ireland) (IE)
- Sir Run Run Shaw Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1007/s12672-025-03496-x
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52