Incidence and risk factors of immune checkpoint inhibitor myocardial and muscle toxicity: a French nationwide study
This pharmaco-epidemiological study assessed >170 000 French patients treated by ICI in real life, establishing the incidence and identifying risk factors of developing ICI myotoxicities, with severity surrogates associated with fatality.
Authors
- Antoine Rozes
- Sandrine Pinto (ORCID: https://orcid.org/0009-0005-7576-1773)
- A. Ajrouche
- Florence Tubach (ORCID: https://orcid.org/0000-0002-7802-944X)
- Yann De Rycke (ORCID: https://orcid.org/0009-0009-1432-2055)
- Joe‐Elie Salem (ORCID: https://orcid.org/0000-0002-0331-3307)
Institutions
- Inserm (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Pitié-Salpêtrière Hospital (FR)
- Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1093/eurheartj/ehaf682
- Citations
- 8
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 8.36