Keto–enol at play: regioisomerism regulated switching in indole-naphthyl Schiff bases
Indole-naphthyl Schiff bases studied in this work show the importance of hydroxyl positions on enol (E)-keto (K) emissions, aggregation-induced emission (AIE), and viscosity-dependent emission properties. Single-crystal X-ray diffraction and computational studies provide insights into the structural properties of the tautomeric species. INpOH-1 and INpOH-2 demonstrated potential for distinguishing normal and cancer cells based on their polarity and viscosity sensitivity.
Authors
- Adarash Kumar Shukla (ORCID: https://orcid.org/0000-0002-8696-3806)
- Anupam Bhattacharya (ORCID: https://orcid.org/0000-0002-0113-5252)
- Ashutosh Mahale (ORCID: https://orcid.org/0000-0002-9238-8262)
- Onkar P. Kulkarni (ORCID: https://orcid.org/0000-0002-8877-0573)
- Pravinkumar Vipparthi
- Savita Choudhary
- Sanjana Panyala
Institutions
- Birla Institute of Technology and Science - Hyderabad Campus (IN)
- Birla Institute of Technology and Science, Pilani (IN)
Publication Details
- Journal
- Physical Chemistry Chemical Physics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cp01939g
- Primary Topic
- Axial and Atropisomeric Chirality Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00