A VALIDATED UV-SPECTROPHOTOMETRIC METHOD FOR VILDAGLIPTIN ASSAY USING GREEN SOLVENT

This study primarily focuses on developing a novel UV method for the assay of vildagliptin in both pure form and pharmaceutical dosage forms.The process involves preparing standard and working solutions of vildagliptin, followed by the analysis of different concentrations of the working solution.The established method is then subjected to validation as per ICH guidelines.The results indicate that the developed method is sensitive and accurate, particularly within the concentration range of 4-24 g/ml.The correlation coefficient (R2) was determined to be 0.999.Notably, there was no interference observed with the excipients present in the formulation.The proposed method holds potential for the analysis of vildagliptin in bulk and formulation, making it suitable for routine analysis

Publication Details

Journal
International Journal of Biology Pharmacy and Allied Sciences
Published
2025-08-30
DOI
https://doi.org/10.31032/ijbpas/2025/14.9.8810
Primary Topic
Analytical Methods in Pharmaceuticals
Type
article
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article

A VALIDATED UV-SPECTROPHOTOMETRIC METHOD FOR VILDAGLIPTIN ASSAY USING GREEN SOLVENT

International Journal of Biology Pharmacy and Allied Sciences
Analytical Methods in Pharmaceuticals
article

A VALIDATED UV-SPECTROPHOTOMETRIC METHOD FOR VILDAGLIPTIN ASSAY USING GREEN SOLVENT

article en

Abstract

This study primarily focuses on developing a novel UV method for the assay of vildagliptin in both pure form and pharmaceutical dosage forms.The process involves preparing standard and working solutions of vildagliptin, followed by the analysis of different concentrations of the working solution.The established method is then subjected to validation as per ICH guidelines.The results indicate that the developed method is sensitive and accurate, particularly within the concentration range of 4-24 g/ml.The correlation coefficient (R2) was determined to be 0.999.Notably, there was no interference observed with the excipients present in the formulation.The proposed method holds potential for the analysis of vildagliptin in bulk and formulation, making it suitable for routine analysis

International Journal of Biology Pharmacy and Allied SciencesVol. 14(9)
Openalex Percentile: Top 74%
Analytical Methods in Pharmaceuticals
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