DEVELOPMENT OF UV-SPECTROPHOTOMETRIC METHOD FOR LORATADINE IN PURE AND DOSAGE FORM

This study primarily focuses on developing a novel UV method for the assay of Loratadine in both pure form and pharmaceutical dosage forms.The process involves preparing standard and working solutions of Loratadine, followed by the analysis of different concentrations of the working solution.The established method is then subjected to validation as per ICH guidelines.The results indicate that the developed method is sensitive and accurate, particularly within the concentration range of 4-24 g/ml.The correlation coefficient (R2) was determined to be 0.999.Notably, there was no interference observed with the excipients present in the formulation.The proposed method holds potential for the analysis of Loratadine in bulk and formulation, making it suitable for routine analysis