Spermidine Reproduces the Anti‐Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal‐Induced Inflammation

In summary, we have identified several metabolites that recapitulate the anti-inflammatory effects of IF and could be used as IF mimetics to prevent microcrystal inflammation.

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Publication Details

Journal
Arthritis & Rheumatology
Published
2025-08-30
DOI
https://doi.org/10.1002/art.43367
Citations
2
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
4.01
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article

Spermidine Reproduces the Anti‐Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal‐Induced Inflammation

Augustin Latourte, Thomas Bardin, Agnès Ostertag, Florence Castelli et al.
2 citations
Arthritis & Rheumatology
Dermatology and Skin Diseases
4.01
article

Spermidine Reproduces the Anti‐Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal‐Induced Inflammation

Augustin Latourte, Thomas Bardin, Agnès Ostertag, Florence Castelli, François Fenaille, Flora Finet, Mylène Zarka, François Brial, Chinh Nghia Pham, Christèle Combes, Pascal Richette, Twinu Wilson Chirayath, Subhabrata Moitra, Hang‐Korng Ea, Céline Chollet, C Leroy
article en
2 citations

Abstract

In summary, we have identified several metabolites that recapitulate the anti-inflammatory effects of IF and could be used as IF mimetics to prevent microcrystal inflammation.

Arthritis & RheumatologyVol. 78(2)
Centre National de la Recherche Scientifique (FR), Université Toulouse III - Paul Sabatier (FR), Inserm (FR), Université Fédérale de Toulouse Midi-Pyrénées (FR), Université Paris Cité (FR), Institut National Polytechnique de Toulouse (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Université Paris-Saclay (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), École Nationale Supérieure des Ingénieurs en Arts Chimiques et Technologiques (FR), Direction de la Recherche Fondamentale (FR), Bioscar (FR), Hôpital Lariboisière (FR), CEA Paris-Saclay (FR), Centre Interuniversitaire de Recherche et d’Ingénierie des Matériaux (FR), MetaboHUB (FR), Hai Phong University of Management and Technology (VN)
Openalex Percentile: Top 6%
Dermatology and Skin Diseases
4.01
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