Automated bimodal pause analysis for acoustic markers of cognitive decline and Alzheimer's disease in connected speech
Pausing in connected speech was investigated as a digital marker of cognitive decline. Bimodal log-normal pause distribution distinguishes between cognitive groups. Short (80-180 ms) and long (> 180 ms) pauses correlate with tau and amyloid.
Authors
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Visar Berisha (ORCID: https://orcid.org/0000-0001-8804-8874)
- Deling He (ORCID: https://orcid.org/0000-0003-4690-6871)
- Julie Liss (ORCID: https://orcid.org/0000-0001-8782-2901)
- Carol Van Hulle
- Lingfeng Xu (ORCID: https://orcid.org/0000-0002-6554-9438)
- Kimberly D. Mueller (ORCID: https://orcid.org/0000-0001-8691-9517)
Institutions
- University of Wisconsin–Madison (US)
- Arizona State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1002/alz.70635
- Primary Topic
- Dysphagia Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Aging