Dermatomyositis associated with malignancy: a case highlighting paraneoplastic syndrome

Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by distinctive cutaneous manifestations and progressive, symmetric proximal muscle weakness. It affects both adults and children, with variable clinical presentations and disease severity. The pathogenesis involves autoimmune mechanisms, including complement-mediated microangiopathy, with a potential association with malignancies in adults. In this case study, we report a case of classical DM with incidence of malignancy. Timely diagnosis and administration of steroid led to better prognosis of the patient.

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Publication Details

Journal
International Journal of Research in Medical Sciences
Published
2025-08-29
DOI
https://doi.org/10.18203/2320-6012.ijrms20252815
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
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article

Dermatomyositis associated with malignancy: a case highlighting paraneoplastic syndrome

Arun Krishnan, Chavan Mayuresh Sanjeev, Jaykaran
International Journal of Research in Medical Sciences
Inflammatory Myopathies and Dermatomyositis
article

Dermatomyositis associated with malignancy: a case highlighting paraneoplastic syndrome

Arun Krishnan, Chavan Mayuresh Sanjeev, Jaykaran
article en

Abstract

Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by distinctive cutaneous manifestations and progressive, symmetric proximal muscle weakness. It affects both adults and children, with variable clinical presentations and disease severity. The pathogenesis involves autoimmune mechanisms, including complement-mediated microangiopathy, with a potential association with malignancies in adults. In this case study, we report a case of classical DM with incidence of malignancy. Timely diagnosis and administration of steroid led to better prognosis of the patient.

International Journal of Research in Medical SciencesVol. 13(9)
Sree Balaji Dental College and Hospital (IN)
Openalex Percentile: Top 69%
Inflammatory Myopathies and Dermatomyositis
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Dermatomyositis associated with malignancy: a case highlighting paraneoplastic syndrome — Arun Krishnan, Chavan Mayuresh Sanjeev, et al. · International Journal of Research in Medical Sciences (2025) | TGRS Research Map | TGRS