Future of Families: Cardiovascular Health Among Young Adults Cohort Study: Rationale, Key Questions, Study Design, and Participant Characteristics
This article describes the rationale, study design and methods, and characteristics of the FF-CHAYA cohort, a novel longitudinal study designed to examine associations of childhood social determinants with young adult cardiovascular health and early arterial injury, as well as potential epigenetic mechanisms that may mediate these associations.
Authors
- Lifang Hou (ORCID: https://orcid.org/0000-0003-4877-0031)
- Hongyan Ning (ORCID: https://orcid.org/0000-0003-1157-6614)
- Iulia Kotenko (ORCID: https://orcid.org/0000-0003-4632-4433)
- Donald M. Lloyd‐Jones (ORCID: https://orcid.org/0000-0003-0847-6110)
- Nicole Katchur (ORCID: https://orcid.org/0000-0002-3936-1917)
- Norrina B. Allen (ORCID: https://orcid.org/0000-0002-6993-4384)
- Susan J. Little (ORCID: https://orcid.org/0000-0002-7645-9737)
- Lisa Schneper (ORCID: https://orcid.org/0000-0002-1365-1000)
- Claudia E. Korcarz (ORCID: https://orcid.org/0000-0001-9691-9027)
- Noreen Goldman (ORCID: https://orcid.org/0000-0003-2865-9491)
- Hacer Gulen Savas (ORCID: https://orcid.org/0009-0007-6187-4456)
- Jessica L. Rooney
- Yinan Zheng (ORCID: https://orcid.org/0000-0002-2006-7320)
- Russell P. Tracy (ORCID: https://orcid.org/0000-0002-0080-2420)
- Colter Mitchell (ORCID: https://orcid.org/0000-0001-9560-1199)
- James H. Stein (ORCID: https://orcid.org/0000-0002-2770-8223)
- Kristin A. Hansen
- Linda Van Horn (ORCID: https://orcid.org/0000-0002-1362-5806)
- Daniel A. Notterman (ORCID: https://orcid.org/0000-0002-8809-8297)
- Elisabeth Tawa
Institutions
- Boston University (US)
- University of Vermont (US)
- Northwestern University (US)
- University of Wisconsin–Madison (US)
- Princeton University (US)
- University of Michigan (US)
- Princeton Public Schools (US)
- Northwestern Medicine (US)
- Institute for Atherosclerosis Research (RU)
- University School (US)
- Institute for Social Research (NO)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1161/jaha.125.042030
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 10.48
Funders
- American Heart Association
- Princeton University
- Northwestern University
- Feinberg School of Medicine
- National Heart, Lung, and Blood Institute