Adjuvant capecitabine in patients with triple-negative breast cancer after neoadjuvant chemotherapy

In this large cohort of patients with TNBC-RD after NAC, omission of adjuvant therapy was common, with less than one-third of patients receiving adjuvant capecitabine. Receipt of adjuvant capecitabine was associated with significantly improved RFS, DRFS, and OS.

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Publication Details

Journal
ESMO Open
Published
2025-08-29
DOI
https://doi.org/10.1016/j.esmoop.2025.105568
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Adjuvant capecitabine in patients with triple-negative breast cancer after neoadjuvant chemotherapy

V. Valero, Qi Jin, Melissa E. Hughes, Ava Strahan et al.
ESMO Open
Breast Cancer Treatment Studies
article

Adjuvant capecitabine in patients with triple-negative breast cancer after neoadjuvant chemotherapy

V. Valero, Qi Jin, Melissa E. Hughes, Ava Strahan, Tonia Parker, Ana C. Garrido-Castro, Agepati S. Raghavendra, S.M. Tolaney, Elizabeth A. Mittendorf, Carlos H. Bárcenas, Timothy King, Julie Vincuilla, P. Tarantino, Kai C. C. Johnson, Melissa Grimm, Nancy U. Lin, Daniel G. Stover, Nabihah Tayob, Danielle Brandes Zakon, Mathew Cherian, Debu Tripathy
article en

Abstract

In this large cohort of patients with TNBC-RD after NAC, omission of adjuvant therapy was common, with less than one-third of patients receiving adjuvant capecitabine. Receipt of adjuvant capecitabine was associated with significantly improved RFS, DRFS, and OS.

ESMO OpenVol. 10(9)
Twitter (United States) (US), Brigham and Women's Hospital (US), The University of Texas MD Anderson Cancer Center (US), Dana-Farber Cancer Institute (US), Dana-Farber Brigham Cancer Center (US), The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 72%
Breast Cancer Treatment Studies
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