Real-world data on adult AML with FLT3-ITD mutation from the Thai acute leukemia working group
In this nationwide real-world study, <i>FLT3</i>-ITD AML was associated with inferior outcomes despite comparable induction therapy. Limited access to FLT3-targeted treatments and stem cell transplantation may contribute to these disparities. Our findings highlight the urgent need for expanding access to molecular testing and targeted therapies in resource-limited settings.
Authors
- Kannadit Prayongratana (ORCID: https://orcid.org/0000-0003-3447-7600)
- Panachai Silpsamrit (ORCID: https://orcid.org/0000-0002-2679-4254)
- Chinadol Wanitpongpun (ORCID: https://orcid.org/0000-0002-9527-4455)
- Supawee Saengboon (ORCID: https://orcid.org/0000-0002-4473-9216)
- Chajchawan Nakhakes (ORCID: https://orcid.org/0000-0001-7158-8313)
- Chantiya Chanswangphuwana (ORCID: https://orcid.org/0000-0002-5258-2140)
- Pimjai Niparuck (ORCID: https://orcid.org/0000-0002-9422-9353)
- Pirun Saelue (ORCID: https://orcid.org/0000-0003-3900-460X)
- Weerapat Owattanapanich (ORCID: https://orcid.org/0000-0002-1262-2005)
- Wasithep Limvorapitak (ORCID: https://orcid.org/0000-0003-1451-7636)
- Jakrawadee Julamanee (ORCID: https://orcid.org/0000-0002-6526-9479)
- Smith Kungwankiattichai (ORCID: https://orcid.org/0000-0001-6072-4025)
- Chantana Polprasert (ORCID: https://orcid.org/0000-0001-6949-4449)
- Ekarat Rattarittamrong (ORCID: https://orcid.org/0000-0002-7819-5544)
- Thanawat Rattanathammethee (ORCID: https://orcid.org/0000-0003-2731-4889)
- Adisak Tantiworawit (ORCID: https://orcid.org/0000-0002-2381-9292)
- Thanakrit Piyajaroenkij (ORCID: https://orcid.org/0000-0002-1683-6297)
- Aimwipa Sasakul
- Dusit Jit-ueakul (ORCID: https://orcid.org/0000-0002-1073-8872)
- Chantrapa Sriswasdi
Institutions
- Thammasat University (TH)
- Prince of Songkla University (TH)
- Siriraj Hospital (TH)
- Chulalongkorn University (TH)
- Khon Kaen University (TH)
- Navamindradhiraj University (TH)
- Phramongkutklao Hospital (TH)
- Chulabhorn Hospital (TH)
- Rajavithi Hospital (TH)
- Ramathibodi Hospital (TH)
- Chiang Mai University (TH)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-29
- DOI
- https://doi.org/10.3389/fonc.2025.1606943
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00