Sea cucumber polypeptide ameliorates aging properties via the brain-gut axis in naturally aging mice
Our findings propose a mechanism whereby SCP might exert geroprotective effects through multimodal regulation of the gut-brain axis and systemic metabolic homeostasis, establishing mechanistic foundations for its translational potential in healthy longevity promotion.
Authors
- Zhiheng Su (ORCID: https://orcid.org/0000-0002-3908-3208)
- Xin Mao (ORCID: https://orcid.org/0000-0001-5220-5292)
- Qinpei Lu
- Hongwei Guo (ORCID: https://orcid.org/0000-0002-4046-2643)
- Lu Lu (ORCID: https://orcid.org/0000-0002-1651-5944)
- Xia Li (ORCID: https://orcid.org/0000-0001-5429-1657)
- Zhaoquan Huang (ORCID: https://orcid.org/0009-0008-2404-5947)
- Han Mo (ORCID: https://orcid.org/0000-0003-1834-1746)
- Chao Feng (ORCID: https://orcid.org/0000-0003-2140-842X)
- Shulin Wu
- Huisha Huang
- Yiwen Shou
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Guangxi University of Chinese Medicine (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1186/s13020-025-01201-2
- Citations
- 1
- Primary Topic
- Echinoderm biology and ecology
- Type
- article
- Field-Weighted Citation Impact
- 2.27
Funders
- Guangxi Key Research and Development Program