Hepatitis C ventriculitis obscured by concurrent methicillin-resistant <i>Staphylococcus aureus</i> infection after ventriculoperitoneal shunt placement: An illustrative case

In patients with chronic HCV, viral reactivation may manifest as protracted ventriculitis in the setting of low-to-normal pressure ventriculomegaly. Providers should be cognizant of serologically covert viral etiologies for post-operative infections and consider preemptive antiviral treatment in patients with aseptic CSF profiles when refractory to empiric antibiotic regimens for more common CNS pathogens.