THE ASSOCIATION OF TOTAL SLEEP DURATION ON HYPERTENSION RISK IN PAKISTAN: A PROSPECTIVE ANALYSIS.

Background:Lack of sleep has been associated with negative cardiovascular events, such as high blood pressure. But evidence in South Asian population is limited.Objective:This prospective study aimed to assess the relationship between total sleep duration and the development of hypertension in adults aged 40-70 years.Study place and duration The study was conducted from January 2023to August 2024 in rural areas of sindh. Methodology The study include adults (697) who didn't have hypertension initially. Researchers tracked who developed hypertension over time and categorized participants based on their reported sleep duration: less than 6 hours, 6-7.9 hours, 8-9.9 hours, or 10 hours or more.Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). Results:70 participants (9.6%) were diagnosed as hypertension at follow-up.Sleeping <6h versus the reference group was associated with significantly higher risk of hypertension (adjusted OR, 1.71; 95% CI, 1.01 to 2.89; P<0.05). A significant association was not observed for longer sleep lengths.Conclusions:Short sleep was independently related to risk of incident hypertension. These results suggestedsleep duration may be an indicator of cardiovascular risk discussing the importance of sleep hygiene to prevent hypertension