ITGA2 Mediates the Resistance of Hepatocellular Carcinoma to Lenvatinib by Activating the AKT/FOXO3A Signaling Pathway

The global incidence of primary liver cancer ranks sixth among malignant tumors, while its mortality rate ranks third and is the second leading cause of cancer-related deaths in China [...].

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Publication Details

Journal
Cancers
Published
2025-08-29
DOI
https://doi.org/10.3390/cancers17172846
Primary Topic
FOXO transcription factor regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

ITGA2 Mediates the Resistance of Hepatocellular Carcinoma to Lenvatinib by Activating the AKT/FOXO3A Signaling Pathway

Bing Xu, Genhua Ye, Xiangnan Liang, Kai Gong et al.
Cancers
FOXO transcription factor regulation
article

ITGA2 Mediates the Resistance of Hepatocellular Carcinoma to Lenvatinib by Activating the AKT/FOXO3A Signaling Pathway

Bing Xu, Genhua Ye, Xiangnan Liang, Kai Gong, Binwen Sun, Ming Zhong, Lian Gong, Liming Wang, Chun Han, Qiuxiang Wang, Zeli Yin, Yuechuan Liu
article en

Abstract

The global incidence of primary liver cancer ranks sixth among malignant tumors, while its mortality rate ranks third and is the second leading cause of cancer-related deaths in China [...].

CancersVol. 17(17)
Sun Yat-sen University (CN), Dalian Medical University (CN), The Seventh Affiliated Hospital of Sun Yat-sen University (CN), Second Affiliated Hospital of Dalian Medical University (CN)
Openalex Percentile: Top 80%
FOXO transcription factor regulation
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ITGA2 Mediates the Resistance of Hepatocellular Carcinoma to Lenvatinib by Activating the AKT/FOXO3A Signaling Pathway — Bing Xu, Genhua Ye, et al. · Cancers (2025) | TGRS Research Map | TGRS