Effect of pH on the Kinetics of Cysteine-to-Cystine Conversion in Thin Films Formed by ESI Microdroplet Deposition
The oxidation of cysteine to cystine was investigated in aqueous thin films generated by the deposition of electrospray ionization (ESI) microdroplets. The confined volume of the thin film promotes the reaction, resulting in up to 80% conversion of cysteine to cystine at a thin film temperature of 40 °C. The pH of the solution is a critical parameter, influencing both the yield and the kinetics of the reaction. Strong reaction acceleration factors in thin film with respect to the bulk were measured.
Authors
- Marta Managò (ORCID: https://orcid.org/0000-0003-4832-0567)
- Chiara Salvitti (ORCID: https://orcid.org/0000-0002-9184-1299)
- Federico Pepi (ORCID: https://orcid.org/0000-0001-6617-8192)
- Andreina Ricci (ORCID: https://orcid.org/0000-0002-6172-0074)
- Anna Troiani (ORCID: https://orcid.org/0000-0002-6412-9407)
- Alessia Di Noi (ORCID: https://orcid.org/0009-0008-2470-7322)
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of the American Society for Mass Spectrometry
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1021/jasms.5c00195
- Primary Topic
- nanoparticles nucleation surface interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00