The application of KI.C57-ras2.0 mouse in the carcinogenicity evaluation of medical devices—carcinogenicity evaluation of a novel hemodialyzer
This new hemodialyzer had no carcinogenicity under this experimental condition. This study also improved the biological evaluation system of medical devices. As an animal model with great application prospects, we believe that KI.C57-ras2.0 mice will be an indispensable model animal for the evaluation of medical devices in the future, and facilitated the marketing of new biomaterials and medical devices.
Authors
- Zhu Meng
- Qianqian Han (ORCID: https://orcid.org/0000-0001-8127-6209)
- Ran Guan (ORCID: https://orcid.org/0000-0001-5787-8656)
- Chenyu Zhao (ORCID: https://orcid.org/0000-0001-8834-5414)
- Fanshan Qiu
- Dandan Chen (ORCID: https://orcid.org/0000-0002-5936-6176)
- Rui Wang (ORCID: https://orcid.org/0000-0003-3825-3620)
- Yuting Chen (ORCID: https://orcid.org/0000-0003-4661-2048)
- Han Wang (ORCID: https://orcid.org/0000-0002-5498-8187)
- Yang Liu (ORCID: https://orcid.org/0000-0003-2626-375X)
- Changjun Mu (ORCID: https://orcid.org/0000-0003-0612-6563)
Institutions
- China Pharmaceutical University (CN)
- Yantai University (CN)
- Blood Center of Zhejiang Province (CN)
- National Institutes for Food and Drug Control (CN)
- Weihai Science and Technology Bureau (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1080/07853890.2025.2549522
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China