Therapeutic Potential of Plumbagin: Redox Modulation and Pathway Inhibition in Cancer and Neuroinflammation

: Aim of this research review is to explore anti-microbial and anti-inflammatory properties of Plumbagin which is a naturally occurring secondary metabolite which is derived from Naphthoquinone which resembles vitamin-K in chemical structure and to observe common challenges currently being faced with plumbagin which ranges from low bio-availibilty to moderate toxicity. In current day Plumbagin is the new red hot frontier in fields of pharmaceutics as latest research has shown its extensive therapeutic activities, including anticancer, anti-inflammatory, antimicrobial, activities and PLB exerts potent antitumor activity by inducing reactive oxygen species (ROS), triggering cell cycle arrest, apoptosis, and autophagy across multiple cancer types such as breast, brain, and hepatocellular carcinoma.